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Zopiclone, zaleplon and zolpidem, three non-benzodiazepine hypnotics, all made the animals to respond as if they had received the benzodiazepine, while a number of other substances, including barbiturates, chloral hydrate, but also the compounds that bind to zopiclone GABAA receptors but not to the α1containing subtypes, failed to do so (Ator, 2005) .
In an operant study on squirrel monkeys, the effect of zopiclone on punished responding but also on unpunished responding and responding maintained by food or shock presentation was very similar to that of chlordiazepoxide, all of its effects being either shifted to the right on the dose-response graphs or completely blocked by flumazenil, a benzodiazepine receptor antagonist, dependent on the dose zopiclone of the latter (Barrett et al . ger stilnoct utslag på benzo stilnoct ibuprofen stilnoct varje natt zopiclone first time zopiklon , 1986) .
zopiclone The discriminative stimulus properties of stereoisomers of zopiclone were recently compared to that of the parent drug in rhesus monkeys (McMahon et al . zopiklon läkemedel stilnoct online beroende av zopiklon stilnoct dosage zimovane 3.75 zopiklon pilum , 2003) .
Both (RS)-zopiclone and (S)-zopiclone substituted for midazolam with similar potencies, whereas the inactive stereoisomer of zopiclone had a weak substitutive effect even at very high doses, and this limited effect could possibly be explained by stereoconversion of the compound into ld50 stilnoct zopiclone what is it used for bivirkninger zopiklon mylan stilnoct nhs imovane eureka the (S)isomer in vivo (see below) .
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